Sedatives can sometimes leave the patient with long-term or short-term amnesia.Lorazepam is one such pharmacological agent that can cause anterograde amnesia.In both types of dependences, finding and using the sedative becomes the focus in life.
While benzodiazepines can put people to sleep but, while asleep, the drugs disrupt sleep architecture: decreasing sleep time, delaying time to REM sleep, and decreasing deep slow-wave sleep (the most restorative part of sleep for both energy and mood).
Some heroin users may take them either to supplement their drug or to substitute for it.
Stimulant users may take sedatives to calm excessive jitteriness.
The long-term use of benzodiazepines may have a similar effect on the brain as alcohol, and are also implicated in depression, anxiety, posttraumatic stress disorder (PTSD), mania, psychosis, sleep disorders, sexual dysfunction, delirium, and neurocognitive disorders (including benzodiazepine-induced persisting dementia which persists even after the medications are stopped).
Additionally, benzodiazepines can indirectly cause or worsen other psychiatric symptoms (e.g., mood, anxiety, psychosis, irritability) by worsening sleep (i.e., benzodiazepine-induced sleep disorder).
Others take sedatives recreationally to relax and forget their worries.